CF568 Annexin V conjugate is Annexin V labeled with our superior red fluorescent dye CF568. Annexin V is a 35-36 kDa protein that has a high affinity for phosphatidylserine (PS). In normal viable cells, PS is located on the cytoplasmic surface of the cell membrane. In apoptotic cells, however, PS is translocated from the inner to the outer leaflet of the plasmic membrane, making itself available for Annexin V binding.
CF568 is a red fluorescent dye (Ex/Em = 562/583 nm) with an excitation spectrum optimally matching the 568 nm line of the Ar-Kr mixed-gas laser. Protein conjugates of the dye are much brighter than those of Alexa Fluor? 568. In addition, the photostability of CF568 is superior to that of Alexa Fluor? 568, making CF568 a much better choice for demanding applications, such as confocal microscopy and single molecule imaging.
For more information, download our Apoptosis, Necrosis and Cell Viability Assays Brochure, CF Dye Selection Guide, and Flow Cytometry Products Brochure.
