CF770 Annexin V conjugate is Annexin V labeled with our superior near-IR fluorescent dye CF770 (Ex/Em = 770/797 nm). Annexin V is a 35-36 kDa protein that has a high affinity for phosphatidylserine (PS). In normal viable cells, PS is located on the cytoplasmic surface of the cell membrane. In apoptotic cells, however, PS is translocated from the inner to the outer leaflet of the plasma membrane, making itself available for Annexin V binding. CF770 Annexin V does not contain azide or other potentially toxic materials, and thus is suitable for in vivo imaging.
